The on-loan Chelsea defender was forced off just before half-time in the 5-2 demolition of Derby with a hamstring injury.
Chris Cohen came off the bench to replace Bertrand on Wednesday night and he is likely to get the nod to deputise at left-back.
Club captain Paul McKenna has recovered from a groin injury but the midfielder missed the Derby game with a virus and remains a slight doubt.
Boss Billy Davies is unlikely to be able to call on David McGoldrick and Dele Adebola (both knee) while fellow striker Dexter Blackstock is a long-term injury absentee after suffering knee ligament damage last month.
Source: PA
Source: PA