Fighting a relegation battle in the Premier League is West Ham's current priority while a surging run up the Championship table means promotion is Forest's goal for the remaining months of the season.
Senior coach Paul Groves told the official West Ham website: "It's very important for us to go out and win any game but obviously the importance and status of the Premier League will take precedence.
"How we select will probably be dictated by what is coming up in terms of fixtures."
Billy Davies meanwhile has said: "I am going to try and get some minutes into legs this weekend.
He added on the official club website: "Players like Paul McKenna and David McGoldrick will come into contention, to mention just two names. There will be one or two others as well."