The two sides started the day in the Championship play-off places with the Reds one point behind the Seasiders but looking to bounce back from last weekend's disappointing defeat against bottom club Yeovil.
New Forest loanee David Vaughan joined the club from Sunderland in midweek, signing a three-month deal, and was handed an immediate start while Billy Davies also recalled Henri Lansbury after suspension to replace Nathaniel Chalobah. Up front, Jamie Mackie came in for Simon Cox.
Visiting boss Paul Ince was again confined to the stands after receiving a touchline ban and was also without suspended defender Jack Robinson.
He was however, able to call on Bradley Orr who missed the match against his parent club Blackburn Rovers last weekend and also made a loan signing during the week with the capture of Manchester United youngster Tyler Blackett to cover for Robinson at left-back.
Both Orr and Blackett started the match with former Forest striker Nathan Tyson on the bench.
1st Half: Both sides enjoyed plenty of attacking possession during the opening 45 minutes but Forest's task was made harder when Djamel Abdoun received a red card 10 minutes before the break. The two sides went in scoreless but with Billy Davies having some reshuffling to do.
2nd Half: Strikers Chopra and Tyson were thrown into the mix by Blackpool as they looked to take advantage of their extra man but the game remained relatively even until Stephen Dobbie broke home hearts with a stoppage time winner.