The Seagulls have taken eight points from as many matches in the Championship so far this season and were frustrated by Blackpool in a goalless draw last time out.
In midweek, while a much-changed Forest were bowing out of the League Cup at Tottenham, Brighton's win away to Burton Albion means they will now go to White Hart Lane in the next round.
Boss Sami Hyppia made nine changes himself and praised his side for their display at the Pirelli Stadium although he told the official Seagulls website: "People say don’t change a winning team, but there will probably be one or two changes on Saturday."
Inigo Calderon's dismissal means he will miss three matches while midfielder Paddy McCourt impressed on his full debut.