Press Association Sport understands that incoming manager Pearce, who will officially take charge at the Sky Bet Championship club on July 1, wants to make former Forest winger Wigley the first addition to his back room team.
Wigley, 52, worked under Pearce during his successful spell in charge of the England Under-21 team and, after approaching Fulham earlier this month, the Reds are confident of concluding a deal for the pair to be reunited at the City Ground.
Wigley leaves with immediate effect after overseeing a successful period for Fulham's youth teams, but following the club's relegation from the Barclays Premier League.
He joined the Cottagers in the summer of 2012 and, under Huw Jennings, played a major role in the development of young players
Last week saw the Under-18 side narrowly defeated 7-6 on aggregate by west London neighbours Chelsea in the FA Youth Cup Final.
Academy director Jennings said via a statement on fulhamfc.com: ''It's very disappointing that Steve has left us, especially after such a successful period for the Under-18s.
''Steve was a great asset to Fulham, but he has received an offer in football that he felt compelled to accept, and impossible for us to persuade him otherwise.
"We wish Steve all the very best and thank him for his contribution during his time here."
Source : PA
Source: PA